Qi OuyangView all speakers
Qi Ouyang, Chang-Jiang special Professor at Peking University, China. Director of the Institute of Condense Matter Physics, School of Physics; associate director of the Center for Quantitative Biology, School of Advanced Interdisciplinary Studies, Peking University. Professor Qi Ouyang is specialized on the nonlinear dynamics and pattern formation research in reaction-diffusion system.
From 1996, he started to study biophysics related researches by applying the concept and method of nonlinear dynamics and stochastic physics in living system. His current interests in biology field include biological regulation network dynamics, bio-microfluidics, and synthetic biology.
The main purpose of synthetic biology is to develop basic biological functional modules, and through rational design, develop man-made biological systems that have predicted useful functions. In this talk, I will discuss two methods in rational design of functional biological circuits: the forward engineering and the reverse engineering. Both methods are proven to be successful in electronic engineering. I will use two synthetic biology researches that conducted in my laboratory at Peking University to illustrate the above principles. The first example is to use forward engineering design to synthesis “Pavlov bacteria” which can perform learning and recalling functions; The second example is to use reverse engineering design to synthesize a cell which has a semi-log dose-response to the environment. These works demonstrate that design principles in electronic engineering can be transplant into synthetic biology, but one should pay special attention to the difference between electronic engineering and biological engineering.