SBICE: Synthetic Biology Integrated Concurrent Engineering

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John Cumbers

UC Santa Cruz / NASA Ames Research Center, United States

Despite ongoing technological and scientific advancements in the field of synthetic biology, one major bottleneck in the development of applications is the design process. The task of identifying the necessary components that need to be stitched together remains a laborious and time consuming activity. Here I outline the implementation of an accelerated design and engineering methodology for synthetic biology. This methodology is known as Integrated Concurrent Engineering (ICE) in the aerospace industry and has been shown to cut NASA’s preliminary design time from nine months to three weeks. Applying Integrated Concurrent Engineering to synthetic biology (SBICE) could significantly speed up the design, build and test cycles. I will discuss the first trial session where SBICE was implemented and show that by applying engineering methodologies to biology we could enhance the way we design genetic circuits, genomes and organisms.